Alkylated components in rat liver ribonucleic acid: a possible index of true biological turnover
نویسندگان
چکیده
منابع مشابه
Ribonucleic Acid Composition of Rat Liver Tumor
Studies on normal tissues have suggested that the ribonucleic acid (RNA) of nuclei, mitochon dna, microsomes, and supernatant fluid isolated from tissue homogenate has a characteristic nu cleotide composition (7, 8, 16), while other data did not support such a view (6). Results obtained in this laboratory revealed, in fact, the occurrence of characteristic ribonucleic acids in rat liver frac ti...
متن کاملLocalization of deoxyribonucleic acid complementary to ribosomal ribonucleic acid and preribosomal ribonucleic acid in the nucleolus of rat liver.
The fraction and distribution of DNA complementary to ribosomal RNA and preribosomal RNA was investigated by the technique of molecular hybridization with the DNA of isolated nucleoli and nuclei of rat liver. Nuclear DNA complementary to ribosomal 18 S RNA and 28 S RNA was 0.014% and 0.032%, respectively. Nucleolar DNA complementary to ribosomal 18 S RNA and 28 S RNA was 0.10% and 0.22%, respec...
متن کاملThe effect of chick-liver ribonucleic acid on amino acid-incorporation systems from rat liver.
1. Rat-liver microsomes, ribonucleoprotein particles and a fraction mainly consisting of microsomal membranes were tested for their ability to incorporate amino acids into protein in the presence of ATP, GTP, phosphoenolpyruvate and pyruvate kinase. Addition of polyuridylic acid or of ribonucleic acid from rat-liver nuclei stimulated the incorporating activities. 2. These protein-synthesizing s...
متن کاملSynthesis of Ribonucleic Acids in Rat Liver
Rats infected with virulent Diplococcuspneumoniae developed a significant increase in the rate of incorporation of labelled orotate into hepatic RNA when compared with pair-fed controls inoculated with heat-killed organisms. The finding was readily detected in rats raised on either a low-protein diet (6% casein) or a diet containing adequate amounts of protein (18% casein). The increase in hepa...
متن کاملTurnover of protein and ribonucleic acid in synaptic subcellular fractions from rat brain.
The time courses of the radioactive labels in subcellular fractions from cerebral cortex of mature rats following intraventricular injection of I%-orotate and 3H-leucine were followed from 4 hours to 12 weeks. Special attention was directed to fractions obtained from nerve endings by sucrose gradient centrifugation. After initial transients, the declines in radioactive labels usually followed f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1971
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj1230034pa